diff --git a/src/plugin/host-process.cpp b/src/plugin/host-process.cpp
index e8c3745c..32cf8c82 100644
--- a/src/plugin/host-process.cpp
+++ b/src/plugin/host-process.cpp
@@ -45,7 +45,10 @@ bp::child launch_host(fs::path host_path, Args&&... args) {
 #else
         host_path,
 #endif
-        std::forward<Args>(args)...);
+        // We'll use vfork() instead of fork to avoid potential issues with
+        // inheriting file descriptors
+        // https://github.com/robbert-vdh/yabridge/issues/45
+        bp::posix::use_vfork, std::forward<Args>(args)...);
 }
 
 HostProcess::HostProcess(boost::asio::io_context& io_context, Logger& logger)
diff --git a/src/plugin/host-process.h b/src/plugin/host-process.h
index 859a8af4..5330adf2 100644
--- a/src/plugin/host-process.h
+++ b/src/plugin/host-process.h
@@ -16,6 +16,9 @@
 
 #pragma once
 
+// Bosot.Process's auto detection for vfork() support doesn't seem to work
+#define BOOST_POSIX_HAS_VFORK 1
+
 #include <boost/asio/local/stream_protocol.hpp>
 #include <boost/asio/streambuf.hpp>
 #include <boost/filesystem.hpp>